A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name INS
Type gene
Species Mus musculus
Tissue NA
Experiment Method qRT-PCR,Immunoblot,other
Up/Down NA
Pro/Anti NA
Funtion Description Zmpste24-null mice, which show accelerated aging and are a reliable model of human Hutchinson-Gilford progeria, exhibit an extensive basal activation of autophagy instead of the characteristic decline in this process occurring during normal aging. We also
Regulation Gene NA
Year 2008
Pubmed ID 18443001
Title Premature aging in mice activates a systemic metabolic response involving autophagy induction.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA