A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name INS
Type gene
Species Caenorhabditis elegans
Tissue oocyte
Experiment Method other
Up/Down NA
Pro/Anti Pro
Funtion Description Reproductive cessation is perhaps the earliest aging phenotype that humans experience. TGF-B Sma/Mab and Insulin/IGF-1 signaling regulate C. elegans reproductive aging by modulating multiple aspects of the reproductive process, including embryo integrity,
Regulation Gene NA
Year 2010
Pubmed ID 20946987
Title TGF-B and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA