A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name AS-NMD
Type alternative splicing
Species Caenorhabditis elegans
Tissue NA
Experiment Method PCR,other
Up/Down Down
Pro/Anti Anti
Funtion Description Due to increased AS, NMD pathway genes are upregulated and knocking down UPF1 Homologue smg-2 suppresses DR lifespan
Regulation Gene NA
Year 2018
Pubmed ID 28824175
Title Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA