A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name KI-67
Type gene
Species Homo sapiens
Tissue human peritoneal mesothelial cells
Experiment Method realtime quantitative PCR;
Up/Down Down
Pro/Anti Pro
Funtion Description Dialysate accelerated senescence of the mesothelial cells as reflected by elongation of their population doubling time, reduced expression of KI-67 gene, and increased B-galactosidase activity.Also, expression of the genes regulating the production of the
Regulation Gene NA
Year 2018
Pubmed ID 30802216
Title L-2-oxothiazolidine-4-carboxylic acids slow down dialysate-induced senescence in human peritoneal mesothelial cells.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA