A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name klotho
Type gene
Species Mus musculus
Tissue A total of 30 mice, with body weight of about 20 g and about 5 weeks old
Experiment Method Western blot;RNA isolation and RT-PCR;
Up/Down Up
Pro/Anti Anti
Funtion Description The glycoprotein significantly increase the expression of anti-aging gene klotho in mice kidney. The results suggested that the anti-aging mechanism of FPZ might be achieved by improving the klotho gene expression and repairing the renal function.In addit
Regulation Gene NA
Year 2018
Pubmed ID 30055279
Title Studies on the anti-aging activity of a glycoprotein isolated from Fupenzi (Rubus chingii Hu.) and its regulation on klotho gene expression in mice kidney.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA