A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name klotho
Type gene
Species Rat Rattus
Tissue Male 3-month-old (weight, 320-350 g) SD rats
Experiment Method RT-qPCR;Western blot
Up/Down Up
Pro/Anti Anti
Funtion Description Kaplan-Meier curve analysis demonstrated that aerobic exercise significantly improved rat survival (P<0.001). The ROS levels in rat brain and kidney tissues were decreased in the aerobic exercise groups compared with the control group (P<0.05). In additio
Regulation Gene NA
Year 2018
Pubmed ID 30233703
Title Aerobic exercise-stimulated Klotho upregulation extends life span by attenuating the excess production of reactive oxygen species in the brain and kidney.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA