A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name klotho
Type gene
Species Homo sapiens
Tissue nerve
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description Multiple lines of evidence show that the anti-aging and cognition-enhancing protein Klotho fosters neuronal survival, increases the anti-oxidative stress defense, and promotes remyelination of demyelinated axons.
Regulation Gene NA
Year 2018
Pubmed ID 29352444
Title Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA