Details
| Name | klotho |
| Type | gene |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | PCR,other |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | Overexpression of the putative hormone Klotho in mice extends life span and concomitantly impairs insulin action.In contrast, deletion of Klotho results in a phenotype suggestive of accelerated aging. |
| Regulation Gene | NA |
| Year | 2008 |
| Pubmed ID | 17928362 |
| Title | Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 4 null mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |