Details
| Name | klotho |
| Type | gene |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | In mice a defect of Klotho gene expression results in multiple aging-like phenotypes including short lifespan, osteoporosis and atherosclerosis, while its over-expression suppresses aging and extends lifespan. Contrasting data have been reported as far as |
| Regulation Gene | NA |
| Year | 2010 |
| Pubmed ID | 19421891 |
| Title | The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |