| Name |
LEF-1
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
lung
|
| Experiment Method |
PCR, Flow cytometry assay, Western blot, Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Down-regulated LEF-1 retarded and HU-308 accelerated cell senescence, These findings provided evidence to the idea that down-regulating LEF-1 retarded and HU-308 accelerated cell senescence.
|
| Regulation Gene |
NA
|
| Year |
2018
|
| Pubmed ID |
30372893
|
| Title |
LEF-1 gene silencing inhibits pulmonary vascular remodeling and occurrence of pulmonary arterial hypertension through the B-catenin signaling pathway.
|
| Drug |
0
|
| Disease |
Pulmonary arterial hypertension(PAH)
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
NA
|
| High-throughput |
NA
|