A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name LEP
Type gene
Species Rat Rattus
Tissue blood samples
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Leptin(LEP) induced an approximately 50% decrease in food intake compared with saline controls, an approximately 50% decrease in visceral fat, and improved hepatic (fourfold) and peripheral (30%) insulin action (euglycemic hyperinsulinemic clamp technique
Regulation Gene NA
Year 2002
Pubmed ID 12023258
Title Aging is associated with resistance to effects of leptin on fat distribution and insulin action.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA