A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name leptin
Type gene
Species Rat Rattus
Tissue adipose tissue
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Aged rats also had significantly higher leptin expression and leptin protein concentration in their quadricep muscles than young rats. Our results suggest that elevated leptin levels due to aging cause ectopic inflammation through IL-6 in the skeletal mus
Regulation Gene NA
Year 2019
Pubmed ID 31077169
Title Elevated leptin levels induce inflammation through IL-10 in skeletal muscle of aged female rats
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA