Details
| Name | LMNA |
| Type | gene |
| Species | Homo sapiens |
| Tissue | Fibroblasts |
| Experiment Method | RT-PCR,Immunoblot,other |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | Numerous mutations in the human A-type lamin gene (LMNA) cause the premature aging disease, progeria. Some of these are located in the alpha-helical central rod domain required for the polymerization of the nuclear lamins into higher order structures. Pat |
| Regulation Gene | NA |
| Year | 2009 |
| Pubmed ID | 19926845 |
| Title | A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | 1 |
| High-throughput | NA |