| Name |
MBP-1
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
Human foreskin fibroblasts (HFF)
|
| Experiment Method |
PCR, Flow cytometry assay, Western blot, Immunofluorescence
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Knockdown of MBP-1 in HFF (HFF-MBPsi-4) resulted in an induction of premature senescence, displayed flattened cell morphology, and increased senescence-associated beta-galactosidase activity. Senescent fibroblasts exhibited enhanced expression of phosphor
|
| Regulation Gene |
NA
|
| Year |
2008
|
| Pubmed ID |
18852884
|
| Title |
Knockdown of MBP-1 in Human Foreskin Fibroblasts Induces p53-p21 Dependent Senescence
|
| Drug |
0
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|