A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name 7p21
Type gene
Species Homo sapiens
Tissue lymph
Experiment Method PCR,other
Up/Down Up
Pro/Anti Pro
Funtion Description Variants associated with disease risk correlate with increased expression of the 7p21 gene TMEM106B and no other genes; co- Localization analyses implicated a common causal variant underlying both association with aging and association with TMEM106B expre
Regulation Gene NA
Year 2017
Pubmed ID 29056226
Title A Dementia-Associated Risk Variant nearTMEM106BAlters Chromatin Architecture and Gene Expression
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA