A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MECP2
Type gene
Species Mus musculus
Tissue NA
Experiment Method Western blot
Up/Down NA
Pro/Anti Anti
Funtion Description We found that MECP2 deficiencies lead to senescence and impaired mitochondrial energy production.MSCs from Mecp2Mice Showed a Lower Degree of Proliferation and Apoptosis and Are Prone to Senescence+/-.
Regulation Gene NA
Year 2019
Pubmed ID 31117273
Title Senescence Phenomena and Metabolic Alteration in Mesenchymal Stromal Cells from a Mouse Model of Rett Syndrome.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA