A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MECP2
Type gene
Species Homo sapiens
Tissue GM17567;GM07982
Experiment Method RT-PCR
Up/Down Down
Pro/Anti Anti
Funtion Description To determine the role for mutations of MECP2 in Rett syndrome, we generated isogenic lines of human induced pluripotent stem cells, neural progenitor cells, and neurons from patient fibroblasts with and without MECP2 expression in an attempt to recapitula
Regulation Gene NA
Year 2018
Pubmed ID 29742391
Title Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE107399