A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name mev-1
Type gene
Species Caenorhabditis elegans
Tissue CL4176 strain
Experiment Method quantitative PCR;Fluorescence measurements;High performance liquid chromatography (HPLC)
Up/Down Up
Pro/Anti Anti
Funtion Description Gene-specific mutant studies showed that LJ-E-mediated lifespan extension was dependent on mev-1, daf-2, daf-16, and hsf-1, but not eat-2 genes. LJ-E could upregulate stress-inducible genes, viz., hsp-16.2, sod-3 and mtl-1. we observed that LJ-E could rem
Regulation Gene NA
Year 2018
Pubmed ID 30266681
Title Lonicera japonica extends lifespan and healthspan in Caenorhabditis elegans
Drug Lonicera japonica (LJ)
Disease NA
Environment Factors oxidation and thermal stresses
Circulating NA
Variant NA
High-throughput NA