A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name mTERT
Type gene
Species Mus musculus
Tissue mouse embryonic fibroblasts
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Here, we report the generation and characterization of transgenic mice that express the catalytic subunit of telomerase (mTERT) at high levels in a broad variety of tissues. Expression of mTERT conferred increased telomerase enzymatic activity in several
Regulation Gene NA
Year 2002
Pubmed ID 12034875
Title Constitutive telomerase expression promotes mammary carcinomas in aging mice.
Drug NA
Disease mammary cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA