A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NBN
Type gene
Species Homo sapiens
Tissue skin
Experiment Method PCR,other
Up/Down Up
Pro/Anti Pro
Funtion Description The majority of NBS patients are of Central and Eastern European origin and carry the common founder mutation in the NBN (NBS1) gene, and NBS skin fibroblasts grow slowly in culture and enter early into senescence.
Regulation Gene NA
Year 2018
Pubmed ID 29445421
Title Evidence for a pre-malignant cell line in a skin biopsy from a patient with Nijmegen
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA