A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NDRG1
Type gene
Species Homo sapiens
Tissue NA
Experiment Method RNAi
Up/Down Down
Pro/Anti Anti
Funtion Description We found that suppression of NDRG1 significantly impaired HCC cell growth through inducing extensive cellular senescence of HCC cells both in vitro and in vivo, accompanied by cell cycle arrest at the G1 phase.
Regulation Gene NA
Year 2014
Pubmed ID 24302615
Title Suppressing N-Myc downstream regulated gene 1 reactivates senescence signaling and inhibits tumor growth in hepatocellular carcinoma.
Drug NA
Disease hepatocarcinoma
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA