A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NHR-49
Type gene
Species Caenorhabditis elegans
Tissue NA
Experiment Method RNAi,qPCR
Up/Down Down
Pro/Anti Anti
Funtion Description These NHR-49-dependent, stress-responsive genes are also upregulated in long-lived glp-1/notch receptor mutants, with two of them making critical contributions to the oxidative stress resistance of wild-type and long-lived glp-1 mutants worms.
Regulation Gene NA
Year 2018
Pubmed ID 29508513
Title NHR-49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE107799