A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NKX2-1
Type gene
Species Mus musculus
Tissue NA
Experiment Method other
Up/Down Up
Pro/Anti NA
Funtion Description we demonstrate that brain-specific Sirt1-overexpressing (BRASTO) transgenic mice show significant life span extension in both males and females, and aged BRASTO mice exhibit phenotypes consistent with a delay in aging. These phenotypes are mediated by enh
Regulation Gene NA
Year 2013
Pubmed ID 24011076
Title Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 2 in the DMH and LH.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA