A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NOX2
Type gene
Species Rattus norvegicus
Tissue spinal cord
Experiment Method Immunohistochemistry;RT-PCR;Western blot and Oxyblot
Up/Down Up
Pro/Anti Pro
Funtion Description These results show that middle-aged rats demonstrate increased microglial activation, oxidative stress, and inflammatory gene expression, which may be related to elevated NOX2 expression, and contribute to worsened functional outcome following injury. The
Regulation Gene NA
Year 2017
Pubmed ID 28821269
Title Age exacerbates microglial activation, oxidative stress, inflammatory and NOX2 gene expression, and delays functional recovery in a middle-aged rodent model of spinal cord injury.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA