Details
| Name | NOX4 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | skin |
| Experiment Method | PCR,other |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Inhibition of MMP1 expression through PTEN overexpression is caused by the reduction of NOX4-mediated ROS production. This underlines the important role of PTEN/NOX4 in replicative-induced MMP1 expression and suggests that the regulation of NOX4/ROS by PT |
| Regulation Gene | NA |
| Year | 2017 |
| Pubmed ID | 28557373 |
| Title | PTEN inhibits replicative senescence-induced MMP-1 expression by regulating NOX4-mediated ROS in human dermal fibroblasts. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |