A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NOX4
Type gene
Species Homo sapiens
Tissue MCF12A
Experiment Method RT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description NOX4 was also overexpressed in ovarian tumors. Overexpression of NOX4 in normal breast epithelial cells resulted in cellular senescence, resistance to apoptosis, and tumorigenic transformation. Overexpression of NOX4 in already transformed breast tumor ce
Regulation Gene NA
Year 2010
Pubmed ID 20523116
Title NADPH oxidase 4 is an oncoprotein localized to mitochondria
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA