Details
| Name | NR2E1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | RNAi,RT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Ectopic NR2E1 expression inhibits cellular senescence, extending cellular lifespan in fibroblasts via CBX7-mediated regulation of p16(INK4a) and direct repression of p21(CIP1). |
| Regulation Gene | NA |
| Year | 2015 |
| Pubmed ID | 25328137 |
| Title | The nuclear receptor NR2E1/TLX controls senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |