| Name |
NR4A2
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
brain
|
| Experiment Method |
Quantitative RT-PCR,Chromatin immunoprecipitation
|
| Up/Down |
down
|
| Pro/Anti |
Anti
|
| Funtion Description |
In conclusion, we found that learning-induced Nr4a2, but not Nr4a1, is impaired in the dorsal hippocampus of rats and mice with age-related memory deficits. Further, Nr4a2 expression is limited in the aged brain through the repressive histone deacetylase
|
| Regulation Gene |
NA
|
| Year |
2019
|
| Pubmed ID |
31000586
|
| Title |
HDAC3-mediated repression of the Nr4a family contributes to age-related impairments in long-term memory.
|
| Drug |
NA
|
| Disease |
age-related cognitive impairments
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|