| Name |
Nrf2
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
brain
|
| Experiment Method |
Western blot, Immunohistochemistry, immunofluorescence
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
Nrf2 levels decrease as a function of age, and reduced Nrf2 levels have been reported in postmortem human brains and animal models of AD. Our data suggest a clear link between Nrf2 and AD-mediated cognitive decline and further strengthen the connection be
|
| Regulation Gene |
NA
|
| Year |
2017
|
| Pubmed ID |
29036636
|
| Title |
Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer's disease
|
| Drug |
null
|
| Disease |
Alzheimer's disease
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|