| Name |
ABI3BP
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
7 normal thyroid tissues, 21 follicular thyroid adenomas, 14 Hurthle cell adenomas, 15 follicular thyroid carcinomas, 6 Hurthle cell carcinomas and 18 papillary thyroid carcinomas.
|
| Experiment Method |
qPCR;Western blot
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
We not only observed that ABI3 expression is reduced or lost in most carcinomas but also that there is a positive correlation between ABI3 and ABI3BP expression. Ectopic expression of ABI3 was sufficient to lead to a lower transforming activity, reduced t
|
| Regulation Gene |
NA
|
| Year |
2011
|
| Pubmed ID |
21223585
|
| Title |
ABI3 ectopic expression reduces in vitro and in vivo cell growth properties while inducing senescence.
|
| Drug |
NA
|
| Disease |
thyroid cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|