| Name |
p15ink4b
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
human glioma cell lines U251 MG, U373 MG, and T98G
|
| Experiment Method |
other
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Thus, we conclude thatoverexpressionof p15 has a similar ability to inhibitcellproliferation, to causereplicativesenescence, and to inhibittelomeraseactivityas p16 ingliomacells with an intact RB protein pathway.
|
| Regulation Gene |
NA
|
| Year |
2000
|
| Pubmed ID |
10939591
|
| Title |
Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|