Details
| Name | ACBP |
| Type | gene |
| Species | Caenorhabditis elegans |
| Tissue | Caenorhabditis elegans |
| Experiment Method | qPCR;Western blotting;Analysis of fatty acid composition by GLC;Autophagy assay;ER stress survival assay;Oil Red O staining |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Our work extends toC. elegansthe role of ACBP in aging, implicates HIF-1 in the increase of lifespan ofmaa-1-deficient worms, and sheds light on the anti-aging function of HIF-1. Given that both ACBP and HIF-1 are highly conserved, our results suggest the |
| Regulation Gene | NA |
| Year | 2017 |
| Pubmed ID | 28758895 |
| Title | HIF-1-dependent regulation of lifespan in Caenorhabditis elegans by the acyl-CoA-binding protein MAA-1 |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |