Details
| Name | p16 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | Human diploid fibroblasts (HDFs) |
| Experiment Method | SA B-galactosidase staining;Western-blot;RNA interference and transfection;MTT; |
| Up/Down | Up |
| Pro/Anti | NA |
| Funtion Description | H2O2 markedly induced BLVRA activity in young HDFs, but not in senescent HDFs. Additionally, depletion of BLVRA reduced the H2O2-dependent induction of heme oxygenase-1 (HO-1) in young HDFs, but not in senescent cells, suggesting an aging-dependent differ |
| Regulation Gene | NA |
| Year | 2011 |
| Pubmed ID | 21099244 |
| Title | Biliverdin reductase A in the prevention of cellular senescence against oxidative stress. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |