Details
| Name | p16INK4a |
| Type | gene |
| Species | Mus musculus |
| Tissue | male ACE2KO mice and their wild-type littermates. |
| Experiment Method | quantitative real-time PCR;Histochemistry |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | p16INK4a, a senescence-associated gene, and central nuclei of myofibers increased in middle-aged, but not younger ACE2KO mice. p16INK4a and central nuclei increased in TA muscles of older wild-type mice, but the differences between ACE2KO and wild-type mi |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 30207087 |
| Title | Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |