A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name P16INK4a
Type gene
Species Homo sapiens
Tissue cell lines pCMVLac1,pOPRSVI,pOPRSVI-hSNF5-FLAG
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Overexpression of p16(INK4a) mimics the effect of hSNF5 induction and leads to cellular senescence
Regulation Gene NA
Year 2004
Pubmed ID 14604992
Title P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA