Details
| Name | P16INK4a |
| Type | gene |
| Species | Homo sapiens |
| Tissue | GIST882;GIST430;GIST48;GIST-T2 |
| Experiment Method | RT-PCR;Western blot |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Patients exhibiting a high Bmi-1 expression in the GIST tissues had lower survival rates than those with low Bmi-1 expression. In comparison with the control group, P14ARF, and p16lnk4A were up-regulated, while cyclinD 1 and CDK4 were down-regulated, cell |
| Regulation Gene | NA |
| Year | 2017 |
| Pubmed ID | 29042141 |
| Title | Involvement of Bmi-1 gene in the development of gastrointestinal stromal tumor by regulating p16Ink4A/p15ARF gene expressions: An in vivo and in vitro study. |
| Drug | NA |
| Disease | gastrointestinal stromal tumor |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |