A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p19
Type gene
Species Mus musculus
Tissue Male ICR mice
Experiment Method Quantitative PCR;Senescence-Associated B-Galactosidase (SA-B-Gal) Staining
Up/Down Up
Pro/Anti Pro
Funtion Description We found that D-gal treatment induced noticeably aging-related changes such as reducing thymus coefficients, increasing the pathological injury and cellular senescence of liver, spleen, and hippocampus, as well as an increase in cyclin-dependent kinase in
Regulation Gene NA
Year 2018
Pubmed ID 30598725
Title Matrine Attenuates D-Galactose-Induced Aging-Related Behavior in Mice via Inhibition of Cellular Senescence and Oxidative Stress.
Drug MAT and VE
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA