A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p21
Type gene
Species Homo sapiens
Tissue human dermal microvascular endothelial cells (HDMEC
Experiment Method Western blot
Up/Down Up
Pro/Anti Pro
Funtion Description p16 and p21 were only weakly expressed in early passage HDMEC but both were strongly expressed in senescent cells .
Regulation Gene NA
Year 1997
Pubmed ID 9160882
Title Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA