A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p27
Type gene
Species Homo sapiens
Tissue human dermal microvascular endothelial cells (HDMEC
Experiment Method Western blot
Up/Down Up
Pro/Anti Pro
Funtion Description p27/Kip1 was moderately expressed in senescent HDMEC but at very low or undetectable levels in both early passage cells cultured without VPF/VEGF and in late passage cells cultured with VPF/VEGF.
Regulation Gene NA
Year 1997
Pubmed ID 9160882
Title Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA