A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p38
Type gene
Species Mus musculus
Tissue mouse embryonic fibroblasts
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description We demonstrate that p38 mitogen-activated protein kinase (MAPK) plays important causative roles in senescent cells following telomere shortening, Ras-Raf activation, oxidative stress or inappropriate culture conditions. We also show that papilloma virus E
Regulation Gene NA
Year 2003
Pubmed ID 12581156
Title Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA