Details
| Name | p53 |
| Type | gene |
| Species | Mus musculus |
| Tissue | rat pancreatic cells |
| Experiment Method | real-time PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | It was revealed that ALA reduces and controls the effects of aging on beta cells mainly by suppressing p38 and p53 at the gene level (P<0.001 and P<0.01), respectively, reducing reactive oxygen species (P<0.001) and enhancing levels of thiols (P<0.05) com |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29696608 |
| Title | Regulation of aging and oxidative stress pathways in aged pancreatic islets using alpha-lipoic acid |
| Drug | alpha-lipoic acid (ALA) |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |