A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p53
Type gene
Species Fattening Wagyu steers
Tissue muscle, bone, and fat of fattening Wagyu steers
Experiment Method RNA isolation and real-time PCR;SA-Bgal staining;Immunohistochemistry;
Up/Down Up
Pro/Anti Pro
Funtion Description The positive reaction of senescence marker SA-Bgal activity was observed in visceral adipose tissue. In contrast, the activity of SA-Bgal in subcutaneous and intramuscular adipose tissues were low. The expression of p53 gene, the master regulator of cellu
Regulation Gene NA
Year 2018
Pubmed ID 30111687
Title Fat depot-specific differences of macrophage infiltration and cellular senescence in obese bovine adipose tissues.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA