A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p53
Type gene
Species Mus musculus
Tissue NA
Experiment Method western blot
Up/Down Up
Pro/Anti NA
Funtion Description Our findings suggest that p53 accumulation and heparanase overexpression in senescent endothelial cells are critically involved in mediating the increased risk of venous thrombosis with age
Regulation Gene NA
Year 2018
Pubmed ID 29891592
Title The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice.
Drug NA
Disease Venous thromboembolism
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA