A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p53
Type gene
Species Homo sapiens
Tissue HeLa;HCT116
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description P53 mediates the DNA damage response (DDR) by regulating the expression of genes implicated in cell cycle arrest, senescence, programmed cell death (PCD), and metabolism. Herein we demonstrate that human alkaline ceramidase 2 (ACER2) is a novel transcript
Regulation Gene NA
Year 2018
Pubmed ID 29229990
Title Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA