Details
| Name | p53 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | human bladder carcinoma cell line |
| Experiment Method | Immunoblot;Immunocytochemistry;Northern Blot |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Here we show, using an inducible p53 expression system, that wild-type p53 overexpression in EJ bladder carcinoma cells, which have lost functional p53, triggers the rapid onset of G1 and G2/M growth arrest associated with p21 up-regulation and repression |
| Regulation Gene | NA |
| Year | 1997 |
| Pubmed ID | 9275177 |
| Title | Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53 |
| Drug | NA |
| Disease | bladder cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |