A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p53
Type gene
Species Homo sapiens
Tissue NA
Experiment Method PCR,ChIPs
Up/Down NA
Pro/Anti Pro
Funtion Description Overexpression of E2F1 induces premature S-phase entry and often results in apoptosis. Similarly to p53, E2F1 is stabilized and activated by DNA damage
Regulation Gene NA
Year 2006
Pubmed ID 16892051
Title Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA