| Name |
p53
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
normal human diploid broblasts (HDF)
|
| Experiment Method |
Western blot
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
Escape from senescence can be conferred by loss of function of the tumour suppressor gene products p53 and pRb.
|
| Regulation Gene |
NA
|
| Year |
2002
|
| Pubmed ID |
12082615
|
| Title |
Sequential extension of proliferative lifespan in human fibroblasts induced by over-expression of CDK4 or 6 and loss of p53 function.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|