A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p53
Type gene
Species Homo sapiens
Tissue EJ human bladder carcinoma cell line
Experiment Method other
Up/Down Up
Pro/Anti Pro
Funtion Description These findings provide direct evidence that p53 overexpression can activate the rapid onset of senescence in tumor cells.
Regulation Gene NA
Year 1997
Pubmed ID 9275177
Title Wild-type p53 triggers a rapid senescence program in human tumor cells lackingfunctionalp53
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA