| Name |
p55-gag
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
BM cells
|
| Experiment Method |
Flow cytometric analysis;Colony forming unit (CFU) assay;RT-PCR;immunosorbent assay
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
In conclusion, senescence induced by p55-gag resulted in decreased hematopoietic support function of BMSCs through reducing a series of hematopoietic cytokine expression.
|
| Regulation Gene |
NA
|
| Year |
2017
|
| Pubmed ID |
28544005
|
| Title |
HIV-1 p55-gag protein induces senescence of human bone marrow mesenchymal stem cells and reduces their capacity to support expansion of hematopoietic stem cells in vitro.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|