Details
| Name | p73 |
| Type | gene |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | qRT-PCR |
| Up/Down | Down |
| Pro/Anti | NA |
| Funtion Description | The depletion of p73 not only reduces early-stage apoptotic frequency (4-6hpi), but also significantly increases later-stage DNA DSB accumulation (48hpi), leading to cell cycle arrest in the G2 phase and, ultimately, cell senescence. |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29511339 |
| Title | p73 coordinates with delta 133p53 to promote DNA double-strand break repair. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |